Dendreon

Dendreon Pharmaceuticals LLC
Company typePrivate
Nasdaq: DNDN
IndustryBiomedicine
FounderWilliam A. Haseltine
Edgar Engleman
Samuel Strober
Headquarters
Seal Beach, California
,
U.S.
ProductsProvenge
ServicesProvenge
Number of employees
650
ParentSanpower Group, Nanjing, CN
Websitedendreon.com

Dendreon Pharmaceuticals LLC is a biotechnology company. Its lead product, Provenge (known generically as sipuleucel-T), is an immunotherapy for prostate cancer. It consists of a mixture of the patient's own blood cells (autologous, with dendritic cells thought to be the most important) that have been incubated with the Dendreon PAP-GM-CSF fusion protein. Phase III clinical trial results demonstrating a survival benefit for prostate cancer patients receiving the drug were presented at the AUA meeting on April 28, 2009.[1] After going through the approval process, Provenge was given full approval by the FDA on April 29, 2010.[2] Dendreon's stock value fell 66% on August 4, 2011, after abandoning its forecast for its debut drug Provenge.[3]

In November 2014, Dendreon filed for Chapter 11 bankruptcy protection and shortly afterwards announced that it had reached agreements on the terms of a financial restructuring with certain bond holders.[4]

On February 20, 2015, Valeant Pharmaceuticals received approval to purchase all Dendreon assets. On January 9, 2017 Sanpower Group agrees to acquire Dendreon from Valeant for $819.9 million [5] In June 2017, Sanpower Group, a Chinese conglomerate, purchased Dendreon from Valeant for $820 million.[6]

  1. ^ "AUA IMPACT Trial Presentation Summary" (PDF). Archived from the original (PDF) on 2011-10-01. Retrieved 2009-04-29.
  2. ^ "UPDATE 3-U.S. FDA OKs Dendreon's prostate cancer vaccine". Reuters. 29 April 2010. Retrieved 2010-05-02.
  3. ^ Berkrot, Bill (4 August 2011). "Dendreon plunges as Provenge prospects wither". Reuters. Retrieved 2011-08-04.
  4. ^ "Dendreon files for Chapter 11 bankruptcy" (Press release). Reuters. 10 November 2014.
  5. ^ "Valeant to sell Dendreon unit to China's Sanpower for $820 million". Reuters. 1 January 2017. Retrieved Mar 19, 2019.
  6. ^ "Sanpower Group Completes the Acquisition of Dendreon from Valeant". PR Newswire. 29 June 2017.