| Dense granule | |
|---|---|
 Dense granules shown in a platelet | |
| Details | |
| Identifiers | |
| Latin | granulum delta |
| TH | H2.00.04.1.03006 |
| Anatomical terminology | |
Dense granules (also known as dense bodies or delta granules) are specialized secretory organelles. Dense granules are found only in platelets and are smaller than alpha granules.[1] The origin of these dense granules is still unknown, however, it is thought that may come from the mechanism involving the endocytotic pathway.[2] Dense granules are a sub group of lysosome-related organelles (LRO). There are about three to eight of these in a normal human platelet.[3]
- ^ Michelson, A. D. (2013). Platelets (Vol. 3rd ed). Amsterdam: Academic Press.
- ^ Ambrosio, A. L., Boyle, J. A., & Di Pietro, S. M. (2012). Mechanism of platelet dense granule biogenesis: study of cargo transport and function of Rab32 and Rab38 in a model system. Blood, 120(19), 4072–4081. doi:10.1182/blood-2012-04-420745
- ^ McNicol, A., & Israels, S. J. (1999). Platelet dense granules: Structure, function and implications for haemostasis doi:10.1016/S0049-3848(99)00015-8