| Deputy Premier of South Australia | |
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| Department of the Premier and Cabinet | |
| Style | The Honourable |
| Member of |
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| Reports to | Premier of South Australia |
| Nominator | Premier of South Australia |
| Appointer | Governor of South Australia on the advice of the premier |
| Term length | At the Governor's pleasure |
| Formation | 26 March 1968 |
| First holder | Des Corcoran |
The deputy premier of South Australia is the second-most senior officer in the Government of South Australia. The deputy premiership is a ministerial portfolio in the Cabinet of South Australia, and the deputy premier is appointed by the governor on the advice of the premier of South Australia.
The current deputy premier since 2022 is Susan Close of the South Australian Division of the Australian Labor Party.