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In medicine, desmoplasia is the growth of fibrous connective tissue.[1] It is also called a desmoplastic reaction to emphasize that it is secondary to an insult. Desmoplasia may occur around a neoplasm, causing dense fibrosis around the tumor,[1] or scar tissue (adhesions) within the abdomen after abdominal surgery.[1]
Desmoplasia is usually only associated with malignant neoplasms, which can evoke a fibrotic response invading healthy tissue. Invasive ductal carcinomas of the breast often have a stellate appearance caused by desmoplastic formations.