Detomidine

Detomidine
Clinical data
AHFS/Drugs.comInternational Drug Names
ATCvet code
Legal status
Legal status
  • Veterinary use only
Pharmacokinetic data
Elimination half-life30 min
Identifiers
  • 4-[(2,3-dimethylphenyl)methyl]-3H-imidazole
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC12H14N2
Molar mass186.258 g·mol−1
3D model (JSmol)
  • Cc2cccc(Cc1cnc[nH]1)c2C
  • InChI=1S/C12H14N2/c1-9-4-3-5-11(10(9)2)6-12-7-13-8-14-12/h3-5,7-8H,6H2,1-2H3,(H,13,14) checkY
  • Key:RHDJRPPFURBGLQ-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Detomidine is an imidazole derivative and α2-adrenergic agonist,[citation needed] used as a large animal sedative, primarily used in horses. It is usually available as the salt detomidine hydrochloride. It is a prescription medication available to veterinarians sold under various trade names.

Currently, detomidine is licensed for use only in horses in the US but it is also licensed for use in cattle in Europe and Australasia.[1]

  1. ^ Clarke, Kathy W.; Hall, Leslie W.; Trim, Cynthia M., eds. (2014). "Principles of sedation, anticholinergic agents, and principles of premedication". Veterinary Anaesthesia. pp. 79–100. doi:10.1016/B978-0-7020-2793-2.00004-9. ISBN 978-0-7020-2793-2.