Dexbrompheniramine

Dexbrompheniramine
Clinical data
Trade names	Drixoril, Conex, Dixaphedrine
AHFS/Drugs.com	Multum Consumer Information
Routes of; administration	Oral
ATC code	R06AB06 (WHO) ;
Legal status
Legal status	CA: OTC; US: OTC;
Pharmacokinetic data
Elimination half-life	25 hours
Identifiers
	IUPAC name (3S)-3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine;
CAS Number	132-21-8 ;
PubChem CID	16960;
IUPHAR/BPS	7588;
DrugBank	DB00405 ;
ChemSpider	16068 ;
UNII	75T64B71RP;
ChEBI	CHEBI:59269 ;
ChEMBL	ChEMBL1201287 ;
CompTox Dashboard (EPA)	DTXSID8022905 ;
ECHA InfoCard	100.004.595
Chemical and physical data
Formula	C16H19BrN2
Molar mass	319.246 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Brc1ccc(cc1)[C@@H](c2ncccc2)CCN(C)C;
	InChI InChI=1S/C16H19BrN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3/t15-/m0/s1 ; Key:ZDIGNSYAACHWNL-HNNXBMFYSA-N ;
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Dexbrompheniramine is an antihistamine with anticholinergic properties^[1] used to treat allergic conditions such as hay fever or urticaria. It is the pharmacologically active dextrorotatory isomer of brompheniramine. It was formerly marketed in combination with pseudoephedrine under the name Drixoral in the US and Canada. It is an alkylamine antihistamine.

Dexbrompheniramine is a first generation antihistamine that reduces the effects of the neurotransmitter histamine in the body; sneezing, itching, watery eyes, and runny nose.

^ Löfkvist T (1978). "A comparative evaluation of oral decongestants in the treatment of vasomotor rhinitis". The Journal of International Medical Research. 6 (1): 56–60. doi:10.1177/030006057800600110. PMID 627306. S2CID 39205584.

[1] Löfkvist T (1978). "A comparative evaluation of oral decongestants in the treatment of vasomotor rhinitis". The Journal of International Medical Research. 6 (1): 56–60. doi:10.1177/030006057800600110. PMID 627306. S2CID 39205584.

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