Diamine N-acetyltransferase

diamine N-acetyltransferase
Spermidine N-acetyltransferase dodekamer, Vibrio cholerae
Identifiers
EC no.2.3.1.57
CAS no.54596-36-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a diamine N-acetyltransferase (EC 2.3.1.57) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + an alkane-alpha,omega-diamine CoA + an N-acetyldiamine

Thus, the two substrates of this enzyme are acetyl-CoA and alkane-alpha,omega-diamine, whereas its two products are CoA and N-acetyldiamine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:alkane-alpha,omega-diamine N-acetyltransferase. Other names in common use include spermidine acetyltransferase, putrescine acetyltransferase, putrescine (diamine)-acetylating enzyme, diamine acetyltransferase, spermidine/spermine N1-acetyltransferase, spermidine N1-acetyltransferase, acetyl-coenzyme A-1,4-diaminobutane N-acetyltransferase, putrescine acetylase, and putrescine N-acetyltransferase. This enzyme participates in urea cycle and metabolism of amino groups.