| Don Diego de Alvarado Huanitzin | |
|---|---|
 | |
| Tlatoani of Tenochtitlan | |
| Reign | 1538 – 1541 |
| Installation | 1538 |
| Predecessor | Pablo Xochiquentzin |
| Successor | Diego de San Francisco Tehuetzquititzin |
| Governor of San Juan Tenochtitlan | |
| In office 1538 – 1541 | |
| Preceded by | Pablo Xochiquentzin |
| Succeeded by | Diego de San Francisco Tehuetzquititzin |
| Tlatoani of Ecatepec | |
| Reign | 1520 – 1538 |
| Predecessor | Chimalpilli II |
| Died | 1541 |
| Spouse | Francisca de Moctezuma |
| Father | Tezozomoctli Acolnahuacatl |
Don Diego de Alvarado Huanitzin (or Panitzin) was a 16th-century Nahua noble. A grandson of Axayacatl, Nephew of tlatoani Moctezuma II. He was initially the tlatoani (ruler) of Ecatepec before becoming tlatoani of Tenochtitlan, as well as its first governor under the colonial Spanish system of government.