Dieulafoy's lesion

Dieulafoy's lesion
Other namesExulceratio simplex Dieulafoy
Blood supply of stomach
Pronunciation
  • "Do-la-foy"
SpecialtyGastroenterology
SymptomsHematemesis, melena, hematochezia, anemia
Usual onset52 years (average age)
CausesAberrant submucosal arteriole
Diagnostic methodUpper endoscopy
TreatmentEndoscopic therapy with endoclip, argon plasma coagulation, electrocautery, epinephrine injection, etc
Prognosis8% mortality[1]
Frequency1.5% of gastrointestinal bleeding

Dieulafoy's lesion (French: [djølafwa]) is a medical condition characterized by a large tortuous artery[2] most commonly in the stomach wall (submucosal) that erodes and bleeds. It can present in any part of the gastrointestinal tract.[3] It can cause gastric hemorrhage[4] but is relatively uncommon. It is thought to cause less than 5% of all gastrointestinal bleeds in adults. It was named after French surgeon Paul Georges Dieulafoy, who described this condition in his paper "Exulceratio simplex: Leçons 1-3" in 1898.[5][6] It is also called "caliber-persistent artery" or "aneurysm" of gastric vessels. However, unlike most other aneurysms, these are thought to be developmental malformations rather than degenerative changes.

  1. ^ Cite error: The named reference Sleisenger was invoked but never defined (see the help page).
  2. ^ Smink, Douglas S. (May 2015). "Schwartz's Principles of Surgery, 10th Edition". Annals of Surgery. 261 (5): 1026. doi:10.1097/sla.0000000000001107. ISSN 0003-4932.
  3. ^ Cite error: The named reference JRCSE was invoked but never defined (see the help page).
  4. ^ Akhras J, Patel P, Tobi M (March 2007). "Dieulafoy's lesion-like bleeding: an underrecognized cause of upper gastrointestinal hemorrhage in patients with advanced liver disease". Dig. Dis. Sci. 52 (3): 722–6. doi:10.1007/s10620-006-9468-7. PMID 17237996.
  5. ^ Cite error: The named reference WhoNamedIt was invoked but never defined (see the help page).
  6. ^ Cite error: The named reference ExulceratioSimplex was invoked but never defined (see the help page).