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| Digestive system neoplasm | |
|---|---|
| Specialty | Oncology  |
Digestive system neoplasms are tumors which affect the digestive system. There are many different and various pathologic classification for digestive system neoplasms. Considering the part of the digestive system that they origin, they are classified as:[1]
In 2020 there were approximately 19.3 million new cancer cases and 10.0 million cancer deaths world-wide; and about 14.7% of the new cases were gastrointestinal cancers.[2] Emerging findings indicate that bile acids have a carcinogenic role throughout the digestive system.[2][3] Excessive exposure of gastrointestinal cells to bile acids may arise as a result of a high fat diet, as well as from increased reflux or restricted bile acid flow.[3]
- ^ Marônek, Martin; Link, René; Monteleone, Giovanni; Gardlík, Roman; Stolfi, Carmine (2020-10-30). "Viruses in Cancers of the Digestive System: Active Contributors or Idle Bystanders?". International Journal of Molecular Sciences. 21 (21): E8133. doi:10.3390/ijms21218133. ISSN 1422-0067. PMC 7663754. PMID 33143318.
- ^ a b Li, S.; Qu, X.; Zhang, L.; Wang, N.; Chen, M.; Zhao, X.; Wang, J.; Lv, H.; Qi, Y.; Zhang, L.; Liu, J.; Shi, Y. (2022). "Serum Total Bile Acids in Relation to Gastrointestinal Cancer Risk: A Retrospective Study". Frontiers in Oncology. 12: 859716. doi:10.3389/fonc.2022.859716. PMC 9213662. PMID 35756666.
- ^ a b Bernstein, H.; Bernstein, C. (2023). "Bile acids as carcinogens in the colon and at other sites in the gastrointestinal system". Experimental Biology and Medicine. 248 (1): 79–89. doi:10.1177/15353702221131858. PMC 9989147. PMID 36408538.