Names | |
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IUPAC name
2-methyl-1-nitro-3-[(tetrahydro-3-furanyl) methyl] guanidine
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Other names
(RS)-1-methyl-2-nitro-3-[(tetrahydro-3-furanyl) methyl] guanidine; MTI-446
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Identifiers | |
3D model (JSmol)
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ChEBI | |
ChemSpider | |
ECHA InfoCard | 100.111.831 |
KEGG | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties[1] | |
C7H14N4O3 | |
Molar mass | 202.214 g·mol−1 |
Melting point | 107.5 |
39.83 g/L | |
Hazards | |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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≥2000 mg/kg (oral, rat and mouse)[1] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Dinotefuran is an insecticide of the neonicotinoid class developed by Mitsui Chemicals for control of insect pests such as aphids, whiteflies, thrips, leafhoppers, leafminers, sawflies, mole cricket, white grubs, lacebugs, billbugs, beetles, mealybugs, and cockroaches on leafy vegetables, in residential and commercial buildings, and for professional turf management.[2] Its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors.
In July 2013, the US state of Oregon temporarily restricted the use of dinotefuran pending the results of an investigation into a large bee kill.[3]
Dinotefuran is also used in veterinary medicine as a flea and tick preventive for dogs and as a flea preventive for cats. It is used in combination with pyriproxifen and/or permethrin.[4][5]