Diploidization

Diploidization is the process of converting a polyploid genome back into a diploid one. Polyploidy is a product of whole genome duplication (WGD) and is followed by diploidization as a result of genome shock.[1][2][3][4] The plant kingdom has undergone multiple events of polyploidization followed by diploidization in both ancient and recent lineages.[1] It has also been hypothesized that vertebrate genomes have gone through two rounds of paleopolyploidy.[5] The mechanisms of diploidization are poorly understood but patterns of chromosomal loss and evolution of novel genes are observed in the process.

  1. ^ a b Conant, G.C., J. A. Birchler, and J. C. Pires Dosage, duplication, and diploidization: clarifying the interplay of multiple models for duplicate gene evolution over time. Current Opinion in Plant Biology 2014, 19: 91–98
  2. ^ Feldman, Moshe and Avraham A. Levy Genome evolution in allopolyploid wheat—a revolutionary reprogramming followed by gradual changes. J. Genet. Genomics 2009, 36: 511–518
  3. ^ Hufton, A. L. and G. Panopoulou Polyploidy and genome restructuring: a variety of outcomes Current Opinion in Genetics & Development 2009, 19: 600–606
  4. ^ Wolfe, Kenneth H. Yesterday’s Polyploids and the Mystery of Diploidization Nat Rev Genet. 2001 May;2(5): 333-41.
  5. ^ Wolfe, Kenneth H. Yesterday's Polyploids and the Mystery of Diploidization Nat Rev Genet. 2001 May;2(5): 333–341.