Dipyridamole

Dipyridamole

Clinical data
Trade names	Persantine, others
AHFS/Drugs.com	Monograph
MedlinePlus	a682830
Routes of administration	By mouth, intravenous
ATC code	B01AC07 (WHO)
Legal status
Legal status	UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability	37–66%[1]
Protein binding	~99%
Metabolism	Liver (glucuronidation)[2]
Elimination half-life	α phase: 40 min, β phase: 10 hours
Excretion	Biliary (95%), urine (negligible)
Identifiers
IUPAC name 2,2',2'',2'''-(4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidine-2,6-diyl)bis(azanetriyl)tetraethanol
CAS Number	58-32-2 Y
PubChem CID	3108
IUPHAR/BPS	4807
DrugBank	DB00975 Y
ChemSpider	2997 Y
UNII	64ALC7F90C
KEGG	D00302 Y
ChEBI	CHEBI:4653 Y
ChEMBL	ChEMBL932 Y
CompTox Dashboard (EPA)	DTXSID6040668
ECHA InfoCard	100.000.340
Chemical and physical data
Formula	C24H40N8O4
Molar mass	504.636 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CCN(CC1)C2=NC(=NC3=C2N=C(N=C3N4CCCCC4)N(CCO)CCO)N(CCO)CCO
InChI InChI=1S/C24H40N8O4/c33-15-11-31(12-16-34)23-26-20-19(21(27-23)29-7-3-1-4-8-29)25-24(32(13-17-35)14-18-36)28-22(20)30-9-5-2-6-10-30/h33-36H,1-18H2 Y Key:IZEKFCXSFNUWAM-UHFFFAOYSA-N Y
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Dipyridamole (trademarked as Persantine and others) is a nucleoside transport inhibitor and a PDE3 inhibitor medication that inhibits blood clot formation^{[3][dead link]} when given chronically and causes blood vessel dilation when given at high doses over a short time.