Disease-modifying antirheumatic drug

Methotrexate
Hydroxychloroquine
Auranofin, a gold salt

Disease-modifying antirheumatic drugs (DMARDs) comprise a category of otherwise unrelated disease-modifying drugs defined by their use in rheumatoid arthritis to slow down disease progression.[1][2] The term is often used in contrast to nonsteroidal anti-inflammatory drugs (which refers to agents that treat the inflammation, but not the underlying cause) and steroids (which blunt the immune response but are insufficient to slow down the progression of the disease).

The term "antirheumatic" can be used in similar contexts, but without making a claim about an effect on the disease course.[3] Other terms that have historically been used to refer to the same group of drugs are "remission-inducing drugs" (RIDs) and "slow-acting antirheumatic drugs" (SAARDs).[4]

  1. ^ "disease-modifying antirheumatic drug" at Dorland's Medical Dictionary
  2. ^ "Disease modifying antirheumatic drugs (DMARDs)". Archived from the original on 2009-04-26. Retrieved 2008-10-22.
  3. ^ "antirheumatic" at Dorland's Medical Dictionary
  4. ^ Buer, Jonas Kure (2015). "A history of the term "DMARD"". Inflammopharmacology. 23 (4): 163–71. doi:10.1007/s10787-015-0232-5. PMC 4508364. PMID 26002695.