Disodium aurothiomalate

Disodium aurothiomalate
Clinical data
Routes of
administration		Intramuscular injection
ATC code
Pharmacokinetic data
Bioavailability0%
ExcretionRenal, very slow
Identifiers
CAS Number
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.151.944 Edit this at Wikidata
Chemical and physical data
FormulaC4H3AuNa2O4S
Molar mass390.07 g·mol−1
3D model (JSmol)
  • monomer: [Na]OC(=O)CC(C(=O)O[Na])S[Au]

  • hexamer: [Na]OC(=O)CC(C(=O)O[Na])S[Au-][S+](C(C(=O)O[Na])C(C(=O)O[Na]))[Au-][S+](C(C(=O)O[Na])C(C(=O)O[Na]))[Au-][S+](C(C(=O)O[Na])C(C(=O)O[Na]))[Au-][S+](C(C(=O)O[Na])C(C(=O)O[Na]))[Au-][S+](C(C(=O)O[Na])C(C(=O)O[Na]))[Au]
  • monomer: InChI=1S/C4H6O4S.Au.2Na/c5-3(6)1-2(9)4(7)8;;;/h2,9H,1H2,(H,5,6)(H,7,8);;;/q;3*+1/p-3
  • Key:VXIHRIQNJCRFQX-UHFFFAOYSA-K
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Disodium aurothiomalate is a chemical compound with the formula AuSCH(CO2Na)CH2CO2Na. In conjunction with its monoprotonated derivative, this coordination complex or closely related species are used to treat rheumatoid arthritis, under the tradename Myochrysine.[1] The thiomalate is racemic in most formulation.

  1. ^ Shaw III CF (September 1999). "Gold-based therapeutic agents". Chemical Reviews. 99 (9): 2589–600. doi:10.1021/cr980431o. PMID 11749494.