Distal intestinal obstruction syndrome

Distal intestinal obstruction syndrome
Small intestine(at center)

Distal intestinal obstruction syndrome (DIOS) involves obstruction of the distal part of the small intestines by thickened intestinal content and occurs in about 20% of mainly adult individuals with cystic fibrosis.[1] DIOS was previously known as meconium ileus equivalent, a name which highlights its similarity to the intestinal obstruction seen in newborn infants with cystic fibrosis.[2] DIOS tends to occur in older individuals with pancreatic insufficiency. Individuals with DIOS may be predisposed to bowel obstruction, though it is a separate entity than true constipation.[2]

  1. ^ Kelly, T; Buxbaum, J (July 2015). "Gastrointestinal Manifestations of Cystic Fibrosis". Digestive Diseases and Sciences (Review). 60 (7): 1903–13. doi:10.1007/s10620-015-3546-7. PMID 25648641. S2CID 25453958.
  2. ^ a b Stringer, David A.; Babyn, Paul S. (2000). Pediatric Gastrointestinal Imaging and Intervention. PMPH-USA. p. 347. ISBN 9781550090796.