Distal myopathy

Distal myopathy
Distal myopathy
Other names	Distal muscular dystrophy
	Red depicts the preferentially affected areas in distal myopathy.
Specialty	Neurology, neuromuscular medicine
Symptoms	Weakness of hands and/or feet
Complications	Cardiomyopathy
Usual onset	Variable
Duration	Lifetime
Types	Classic, myofibrillar myopathy, other
Causes	Genetic mutation of various genes
Diagnostic method	Genetic testing, muscle biopsy
Frequency	Rare

Distal myopathy is a group of rare genetic disorders that cause muscle damage and weakness, predominantly in the hands and/or feet. Mutation of many different genes can be causative. Many types involve dysferlin.^[1]

^ Murakami N, Sakuta R, Takahashi E, et al. (December 2005). "Early onset distal muscular dystrophy with normal dysferlin expression". Brain Dev. 27 (8): 589–91. doi:10.1016/j.braindev.2005.02.002. PMID 16310593. S2CID 28957231.

[pmid16310593-1] Murakami N, Sakuta R, Takahashi E, et al. (December 2005). "Early onset distal muscular dystrophy with normal dysferlin expression". Brain Dev. 27 (8): 589–91. doi:10.1016/j.braindev.2005.02.002. PMID 16310593. S2CID 28957231.

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