Dithranol

Dithranol

Clinical data
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Pregnancy category	AU: B2
Routes of administration	topical
ATC code	D05AC01 (WHO)
Legal status
Legal status	UK: P (Pharmacy medicines)
Pharmacokinetic data
Bioavailability	0%, trace amounts metabolites
Protein binding	0%
Metabolism	absorbed and oxidised within the skin
Elimination half-life	n/a
Excretion	n/a
Identifiers
IUPAC name 1,8-dihydroxy-9,10-dihydroanthracen-9-one
CAS Number	1143-38-0 Y
PubChem CID	2202
ChemSpider	2117 Y
UNII	U8CJK0JH5M
KEGG	D00233 Y
ChEBI	CHEBI:37510 Y
ChEMBL	ChEMBL46469 Y
CompTox Dashboard (EPA)	DTXSID7024538
ECHA InfoCard	100.013.216
Chemical and physical data
Formula	C14H10O3
Molar mass	226.231 g·mol−1
3D model (JSmol)	Interactive image
Melting point	178 °C (352 °F)
SMILES O=C2c1c(O)cccc1Cc3c2c(O)ccc3
InChI InChI=1S/C14H10O3/c15-10-5-1-3-8-7-9-4-2-6-11(16)13(9)14(17)12(8)10/h1-6,15-16H,7H2 Y Key:NUZWLKWWNNJHPT-UHFFFAOYSA-N Y
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Dithranol (INN) or anthralin (USAN and former BAN) is a hydroxyanthrone, anthracene derivative, and is used in medications applied to the skin of people with psoriasis. It is available as creams, ointment or pastes in 0.1 to 2% strengths (Drithocreme, Dithrocream, Zithranol-RR, Micanol, Psorlin, Dritho-Scalp, Anthraforte, Anthranol and Anthrascalp). The terms dithranol and anthralin are sometimes used synonymously.