Hypothesis by Louis Dollo in 1893, which states evolution is not exactly reversible
Dollo's law of irreversibility (also known as Dollo's law and Dollo's principle), proposed in 1893[1] by BelgianpaleontologistLouis Dollo states that, "an organism never returns exactly to a former state, even if it finds itself placed in conditions of existence identical to those in which it has previously lived ... it always keeps some trace of the intermediate stages through which it has passed."[2]
The statement is often misinterpreted as claiming that evolution is not reversible,[3] or that lost structures and organs cannot reappear in the same form by any process of devolution.[4][5] According to Richard Dawkins, the law is "really just a statement about the statistical improbability of following exactly the same evolutionary trajectory twice (or, indeed, any particular trajectory), in either direction".[6]Stephen Jay Gould suggested that irreversibility forecloses certain evolutionary pathways once broad forms have emerged: "[For example], once you adopt the ordinary body plan of a reptile, hundreds of options are forever closed, and future possibilities must unfold within the limits of inherited design."[7]
This principle is classically applied to morphology, particularly of fossils, but may also be used to describe molecular events, such as individual mutations or gene losses.