Dominic Smith may refer to:
- Dominic Smith (author) (born 1971), Australian-American novelist
- Dominic Smith (baseball) (born 1995), American baseball player
- Dominic Smith (gymnast) (born 1993), British acrobatic gymnast
- Dominic Smith (footballer, born 1995), English footballer (forward)
- Dominic Smith (footballer, born 1996), English footballer (defender)
- Dominic Smith, (born 1973), birth name of Dynamite MC, English rapper and emcee