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Trade names | Dectomax, others |
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AHFS/Drugs.com | International Drug Names |
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Routes of administration | Subcutaneous, intramuscular, topical |
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ECHA InfoCard | 100.123.125 |
Chemical and physical data | |
Formula | C50H74O14 |
Molar mass | 899.128 g·mol−1 |
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Doramectin, sold under the brand name Dectomax among others, is a veterinary medication approved by the US Food and Drug Administration (FDA) for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice, and mange mites in cattle.[1][2] It is available as a generic medication.[3] It is available as a combination with levamisole under the brand name Valcor.[4]
It is used for the treatment and control of internal parasitosis (gastrointestinal and pulmonary nematodes), ticks and mange (and other ectoparasites). Doramectin is a derivative of avermectin. Similarly to other drugs of this family, it is produced by fermentation by selected strains of Streptomyces avermitilis followed by chemical modification.[1][2][5] Its spectrum includes: Haemonchus, Ostertagia, Trichostrongylus, Cooperia, and Oesophagostomum species and Dictyocaulus viviparus, Dermatobia hominis, Boophilus microplus, and Psoroptes bovis, among many other internal and external parasites. It is available as an injection and as a topical solution.[1][2]