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Charge Detection Mass Spectrometry (CDMS), a variant of mass spectrometry measures both m/z and charge, affording determination of the mass of ions in a sample. It is an advanced analytical technique used in the field of mass spectrometry. It's particularly powerful for analyzing very large molecules, such as proteins and polymers, with high precision. In CDMS, individual molecules are captured in a trap and then subjected to an electric field. As the molecules move within this field, their charge state is detected with extreme accuracy, often down to single charges. This information about the charge states can then be used to determine the mass of the molecules, providing detailed insights into their structure and composition. CDMS has found applications in various fields including biochemistry, pharmaceuticals, and materials science.