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Cyclome is a term used in systems biology to describe the comprehensive study of the menstrual cycle. The concept of cyclome encapsulates the temporal and dynamic variations that occur both within individual menstrual cycles and between different individuals who menstruate. It extends across various biological modalities, including the phenome, genome, transcriptome, metabolome, and proteome, illustrating their interactions and changes throughout the menstrual cycle.
The cyclome provides a framework for understanding these variations in a holistic manner, offering an alternative to normative descriptions[1][2][3] of the menstrual cycle.[4] By focusing on individual differences and the complex interplay between different omics, the cyclome approach allows for a more personalized and accurate representation of menstrual health. The term was coined as part of the project description for the research project: The Omics Atlas of the Menstrual cycle
- ^ Dickinson, Robert Latou; Belskie, Abram. "Dickinson-Belskie "Norma" model, 1939-1950". collections.countway.harvard.edu. Retrieved 2024-07-02.
- ^ Lundberg-Love, Paula K.; Nadal, Kevin L.; Paludi, Michele A. (2011-11-08). Women and Mental Disorders: [4 volumes]. Bloomsbury Publishing USA. ISBN 978-0-313-39320-4.
- ^ Ussher, Jane M. (2006-01-18). Managing the Monstrous Feminine: Regulating the Reproductive Body (0 ed.). Routledge. doi:10.4324/9780203328422. ISBN 978-0-203-32842-2.
- ^ Wang, Yi-Xin; Arvizu, Mariel; Rich-Edwards, Janet W.; Stuart, Jennifer J.; Manson, JoAnn E.; Missmer, Stacey A.; Pan, An; Chavarro, Jorge E. (2020-09-30). "Menstrual cycle regularity and length across the reproductive lifespan and risk of premature mortality: prospective cohort study". BMJ. 371: m3464. doi:10.1136/bmj.m3464. ISSN 1756-1833. PMC 7526082. PMID 32998909.