| Founded | 2009 |
|---|---|
| Folded | 2018 |
| Country | Serbia |
| Number of teams | 16 (2009–2018) |
| Level on pyramid | 4 |
| Promotion to | Serbian League West |
| Relegation to | Kolubara District League Mačva District League Zlatibor District League |
| Domestic cup(s) | Serbian Cup |
| Last champions | Drina Ljubovija (2017–18) |
Drina Zone League (Serbian: Зонска лига Дрина / Zonska liga Drina) was one of the Serbian Zone League divisions, the fourth tier of the Serbian football league system. It was run by the Football Association of West Serbia.
Founded in 2009, the league was folded in 2018, together with the Dunav Zone League and Morava Zone League. Four new sections were established instead, namely Kolubara-Mačva Zone League, Podunavlje-Šumadija Zone League, Šumadija-Raška Zone League and West Morava Zone League.