Drugs in pregnancy

Women should speak to their doctor or healthcare professional before starting or stopping any medications while pregnant.[1] Drugs taken in pregnancy including over-the counter-medications, prescription medications, nutritional supplements, recreational drugs, and illicit drugs may cause harm to the mother or the unborn child. Non-essential drugs and medications should be avoided while pregnant. Tobacco, alcohol, marijuana, and illicit drug use while pregnant may be dangerous for the unborn baby and may lead to severe health problems and/or birth defects.[2] Even small amounts of alcohol, tobacco, and marijuana have not been proven to be safe when taken while pregnant.[3] In some cases, for example, if the mother has epilepsy or diabetes, the risk of stopping a medication may be worse than risks associated with taking the medication while pregnant. The mother's healthcare professional will help make these decisions about the safest way to protect the health of both the mother and unborn child.[4] In addition to medications and substances, some dietary supplements are important for a healthy pregnancy, however, others may cause harm to the unborn child.[5]

The Food and Drug Administration (FDA) in the United States reports that there are six million pregnancies with at least 50% of the women taking at least one medication.[6] In addition a reported 5–10% of women of childbearing age use alcohol or other addictive substances.[7] Of those who bear children, recreational drug use can have serious consequences to the health of not only the mother, but also the fetus as many medications can cross the placenta and reach the fetus. Some of the consequences on the babies include physical and mental abnormalities, higher risk of stillbirth, neonatal abstinence syndrome (NAS), sudden infant death syndrome (SIDS), low birthweight, and others.[8]

  1. ^ Cite error: The named reference :15 was invoked but never defined (see the help page).
  2. ^ NIH (April 2020). "Substance Use While Pregnant and Breastfeeding". National Institute on Drug Abuse. Archived from the original on 23 June 2020. Retrieved 13 August 2020.
  3. ^ "Tobacco, Alcohol, Drugs, and Pregnancy". www.acog.org. Archived from the original on 20 October 2020. Retrieved 13 August 2020.
  4. ^ Tao, Qiuji; Shen, Yajun; Li, Yang; Luo, Huan; Yuan, Meng; Gan, Jing (2022). "Prenatal exposure to antibiotics and risk of neurodevelopmental disorders in offspring: A systematic review and meta-analysis". Frontiers in Neurology. 13: 1045865. doi:10.3389/fneur.2022.1045865. ISSN 1664-2295. PMC 9732381. PMID 36504646.
  5. ^ Cite error: The named reference :13 was invoked but never defined (see the help page).
  6. ^ Office of the Commissioner (4 September 2019). "Medicine and Pregnancy". FDA. Archived from the original on 10 August 2020. Retrieved 5 August 2020.
  7. ^ Morse B, Gehshan S, Hutchins E (1997). "Screening for Substance Abuse During Pregnancy" (PDF). National Center for Education in Maternal and Child Health. Archived (PDF) from the original on 7 December 2021. Retrieved 22 March 2019.
  8. ^ National Institute on Drug Abuse (2020). "Substance Use While Pregnant and Breastfeeding". National Institute on Drug Abuse. Archived from the original on 23 June 2020. Retrieved 28 July 2020.