Dry eye syndrome | |
---|---|
Other names | Dry eye, keratoconjunctivitis sicca, dry eye disease (DED), keratitis sicca |
![]() | |
Diffuse lissamine green staining in a person with severe dry eye[1] | |
Specialty | Ophthalmology, Optometry |
Symptoms | Dry eyes, irritation, redness, discharge, blurred vision[2] |
Complications | Corneal scarring[2] |
Causes | Contact lenses, meibomian gland dysfunction, pregnancy, Sjögren syndrome, vitamin A deficiency, LASIK surgery, antihistamines, hormone replacement therapy, antidepressants[2][3][4] |
Treatment | Artificial tears, wrap around glasses, changing certain medications[2] |
Medication | Ciclosporin, steroid eye drops[2] |
Frequency | ~20%[5] |
Dry eye syndrome, also known as keratoconjunctivitis sicca, is the condition of having dry eyes.[2] Symptoms include dryness in the eye, irritation, redness, discharge, blurred vision, and easily fatigued eyes. Symptoms range from mild and occasional to severe and continuous.[3] Dry eye syndrome can lead to blurred vision, instability of the tear film, increased risk of damage to the ocular surface such as scarring of the cornea, and changes in the eye including the neurosensory system.[2][6]
Dry eye occurs when either the eye does not produce enough tears or when the tears evaporate too quickly.[2] This can be caused by age, contact lens use, meibomian gland dysfunction,[7] pregnancy, Sjögren syndrome, vitamin A deficiency, omega-3 fatty acid deficiency, LASIK surgery, and certain medications such as antihistamines, some blood pressure medication, hormone replacement therapy, and antidepressants.[2][3][4] Chronic conjunctivitis such as from tobacco smoke exposure or infection may also lead to the condition.[2] Diagnosis is mostly based on the symptoms, though a number of other tests may be used.[8] Dry eye syndrome occasionally makes wearing contact lenses impossible.[2]
Treatment depends on the underlying cause. Artificial tears are usually the first line of treatment. Wrap-around glasses that fit close to the face may decrease tear evaporation.[9] Looking carefully at the medications a person is taking and, if safe, altering the medications may also improve symptoms if these medications are the cause. Some topical medications may be suggested to help treat the condition. The immunosuppressant cyclosporine (ciclosporin) may be recommended to increase tear production and, for short term use, topical corticosteroid medications are also sometimes helpful to reduce inflammation.[6] Another treatment that is sometimes suggested is lacrimal plugs that prevent tears from draining from the surface of the eye.
Dry eye syndrome is a common eye disease.[3] It affects 5–34% of people to some degree depending on the population looked at.[5] Among older people it affects up to 70%.[10] In China it affects about 17% of people.[11] The phrase "keratoconjunctivitis sicca" means "dryness of the cornea and conjunctiva" in Latin[12]