E-4031

E-4031
Clinical data
Other names	(1-[2-(6-methyl-2-pyridyl)ethyl]-4-(4-methylsulfonyl-aminobenzoyl)piperidine)
Identifiers
	IUPAC name N-[4-[1-[2-(6-Methylpyridin-2-yl)ethyl]piperidine-4-carbonyl]phenyl];
CAS Number	113558-89-7 ; 113559-13-0 (dihydrochloride);
PubChem CID	3185;
IUPHAR/BPS	2605;
ChemSpider	3073;
UNII	1L1K8X5DF9;
ChEMBL	ChEMBL327980;
CompTox Dashboard (EPA)	DTXSID00150458 ;
Chemical and physical data
Formula	C21H27N3O3S
Molar mass	401.53 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Cc1cccc(n1)CCN2CCC(CC2)C(=O)c3ccc(cc3)NS(=O)(=O)C;
	InChI InChI=1S/C21H27N3O3S/c1-16-4-3-5-19(22-16)12-15-24-13-10-18(11-14-24)21(25)17-6-8-20(9-7-17)23-28(2,26)27/h3-9,18,23H,10-15H2,1-2H3; Key:SRUISGSHWFJION-UHFFFAOYSA-N;
	(verify)

E-4031 is an experimental class III antiarrhythmic drug that blocks potassium channels of the hERG-type.^[1]

^ Kim I, Boyle KM, Carroll JL (April 2005). "Postnatal development of E-4031-sensitive potassium current in rat carotid chemoreceptor cells". Journal of Applied Physiology. 98 (4): 1469–77. doi:10.1152/japplphysiol.01254.2003. PMID 15591286.