Janssen, E., Building | |
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| Location | 422 1st St., Eureka, California |
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| Coordinates | 40°48′18″N 124°9′59″W / 40.80500°N 124.16639°W |
| Area | 0.1 acres (0.040 ha) |
| Built | 1875 |
| Architectural style | Italianate/California Renaissance |
| Part of | Eureka Old Town Historic District (ID91001523) |
| NRHP reference No. | 73000402[1] |
| Added to NRHP | July 16, 1973 |
The E. Janssen Building at 422 First Street, Eureka, California, is a two-story Italianate commercial building. It was built in 1875 to be a hardware and general merchandise store. In 1973, it was the first building in Eureka to be placed on the United States National Register of Historic Places, and it was listed as a contributing property of the National Register Old Town Eureka Historical District in 1991. From 1998 to 2016, the building housed the HSU First Street Gallery, an art gallery run by Humboldt State University.