| Protein-synthesizing GTPase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Identifiers | |||||||||
| EC no. | 3.6.5.3 | ||||||||
| Alt. names | Elongation factor G, EF-G | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
| Translation elongation factor EFG/EF2 | |
|---|---|
| Identifiers | |
| Symbol | Transl_elong_EFG/EF2 |
| InterPro | IPR004540 |
| SCOP2 | 1n0u / SCOPe / SUPFAM |
| EFG/EF2, domain IV | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | EFG_IV | ||||||||
| Pfam | PF03764 | ||||||||
| Pfam clan | CL0329 | ||||||||
| SMART | SM00889 | ||||||||
| CDD | cd01434 | ||||||||
| |||||||||
EF-G (elongation factor G, historically known as translocase) is a prokaryotic elongation factor involved in mRNA translation. As a GTPase, EF-G catalyzes the movement (translocation) of transfer RNA (tRNA) and messenger RNA (mRNA) through the ribosome.[1]
- ^ Shoji, S; Walker, SE; Fredrick, K (2009). "Ribosomal translocation: one step closer to the molecular mechanism". ACS Chem Biol. 4 (2): 93–107. doi:10.1021/cb8002946. PMC 3010847. PMID 19173642.