EGR4

EGR4
Identifiers
Aliases	EGR4, NGFI-C, NGFIC, PAT133, early growth response 4, Early growth response protein 4, AT133
External IDs	OMIM: 128992; MGI: 99252; HomoloGene: 1485; GeneCards: EGR4; OMA:EGR4 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	73,293,701 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	85,490,571 bp
RNA expression pattern
	Top expressed in
	beta cell; ; gonad; ; Region I of hippocampus proper; ; endothelial cell; ; testicle; ; pancreatic ductal cell; ; putamen; ; Brodmann area 46; ; nucleus accumbens; ; entorhinal cortex;
	Top expressed in
	superior frontal gyrus; ; primary visual cortex; ; urethra; ; female urethra; ; male urethra; ; embryo; ; dentate gyrus of hippocampal formation granule cell; ; spermatocyte; ; cerebellar cortex; ; hippocampus proper;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; metal ion binding; nucleic acid binding; DNA-binding transcription activator activity, RNA polymerase II-specific; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding;
Cellular component	nucleus;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; positive regulation of cell population proliferation; transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II; cellular response to growth factor stimulus;
	Sources:Amigo / QuickGO
Orthologs
	1961
	13656
	ENSG00000135625
	ENSMUSG00000071341
	Q05215
	Q9WUF2
	NM_001965
	NM_020596
	NP_001956
	NP_065621
	Wikidata
View/Edit Human	View/Edit Mouse

Early growth response protein 4 (EGR-4), also known as AT133, is a protein that in humans is encoded by the EGR4 gene.^[5]

EGR-4 is a member of the early growth response (EGF) family of zinc finger transcription factors.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000135625 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000071341 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: early growth response 4".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000135625 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000071341 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: early growth response 4".

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