EHMT1

EHMT1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2IGQ, 2RFI, 3B7B, 3B95, 3FPD, 3HNA, 3MO0, 3MO2, 3MO5, 3SW9, 3SWC, 4I51
Identifiers
Aliases	EHMT1, EUHMTASE1, Eu-HMTase1, FP13812, GLP, GLP1, KMT1D, bA188C12.1, euchromatic histone lysine methyltransferase 1, EHMT1-IT1, KLEFS1
External IDs	OMIM: 607001; MGI: 1924933; HomoloGene: 11698; GeneCards: EHMT1; OMA:EHMT1 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	137,870,016 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	24,919,614 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; left testis; ; right testis; ; left ovary; ; body of uterus; ; right hemisphere of cerebellum; ; skin of leg; ; granulocyte; ; ectocervix; ; right ovary;
	Top expressed in
	hand; ; Rostral migratory stream; ; superior cervical ganglion; ; otolith organ; ; utricle; ; maxillary prominence; ; mandibular prominence; ; tail of embryo; ; foot; ; ganglionic eminence;
	More reference expression data
	n/a
Gene ontology
Molecular function	methyltransferase activity; transferase activity; histone methyltransferase activity (H3-K9 specific); zinc ion binding; C2H2 zinc finger domain binding; histone-lysine N-methyltransferase activity; metal ion binding; histone methyltransferase activity (H3-K27 specific); protein-lysine N-methyltransferase activity; protein binding; p53 binding;
Cellular component	nucleoplasm; chromosome; nucleus; nuclear body;
Biological process	response to fungicide; embryo development; negative regulation of transcription by RNA polymerase II; peptidyl-lysine monomethylation; histone H3-K27 methylation; DNA methylation; methylation; histone H3-K9 methylation; peptidyl-lysine dimethylation; histone lysine methylation; histone methylation; negative regulation of transcription, DNA-templated; negative regulation of G0 to G1 transition; chromatin organization; regulation of embryonic development; positive regulation of cold-induced thermogenesis; regulation of signal transduction by p53 class mediator;
	Sources:Amigo / QuickGO
Orthologs
	79813
	77683
	ENSG00000181090
	ENSMUSG00000036893
	Q9H9B1
	Q5DW34
NM_001145527; NM_024757; NM_001039765; NM_001354259; NM_001354263;
	NM_001354611; NM_001354612
	NM_001012518; NM_001109686; NM_001109687; NM_172545
NP_001138999; NP_079033; NP_001341188; NP_001341192; NP_001341540;
	NP_001341541
	NP_001012536; NP_001103156; NP_001103157; NP_766133
	Wikidata
View/Edit Human	View/Edit Mouse

Euchromatic histone-lysine N-methyltransferase 1, also known as G9a-like protein (GLP), is a protein that in humans is encoded by the EHMT1 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000181090 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000036893 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Euchromatic histone-lysine N-methyltransferase 1". Retrieved 2012-03-04.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000181090 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000036893 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Euchromatic histone-lysine N-methyltransferase 1". Retrieved 2012-03-04.

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