ELOVL5

ELOVL5
Identifiers
Aliases	ELOVL5, HELO1, SCA38, dJ483K16.1, ELOVL fatty acid elongase 5
External IDs	OMIM: 611805; MGI: 1916051; HomoloGene: 41449; GeneCards: ELOVL5; OMA:ELOVL5 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	53,349,179 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	77,891,801 bp
RNA expression pattern
	Top expressed in
	seminal vesicula; ; secondary oocyte; ; lactiferous duct; ; tibia; ; skin of thigh; ; trigeminal ganglion; ; parietal pleura; ; epithelium of nasopharynx; ; spinal ganglia; ; inferior ganglion of vagus nerve;
	Top expressed in
	vestibular membrane of cochlear duct; ; Paneth cell; ; carotid body; ; cumulus cell; ; conjunctival fornix; ; adrenal gland; ; facial motor nucleus; ; substantia nigra; ; stria vascularis; ; anterior horn of spinal cord;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; transferase activity; 3-oxo-arachidoyl-CoA synthase activity; 3-oxo-cerotoyl-CoA synthase activity; fatty acid elongase activity; 3-oxo-lignoceronyl-CoA synthase activity; very-long-chain 3-ketoacyl-CoA synthase activity;
Cellular component	dendritic tree; dendrite; integral component of membrane; cell projection; endoplasmic reticulum membrane; soma; membrane; endoplasmic reticulum; integral component of endoplasmic reticulum membrane;
Biological process	lipid metabolism; fatty acid biosynthetic process; linoleic acid metabolic process; alpha-linolenic acid metabolic process; fatty acid metabolic process; unsaturated fatty acid biosynthetic process; fatty acid elongation, polyunsaturated fatty acid; very long-chain fatty acid biosynthetic process; fatty acid elongation, monounsaturated fatty acid; long-chain fatty-acyl-CoA biosynthetic process; positive regulation of fatty acid biosynthetic process; fatty acid elongation, saturated fatty acid; sphingolipid biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	60481
	68801
	ENSG00000012660
	ENSMUSG00000032349
	Q9NYP7
	Q8BHI7
	NM_021814; NM_001242828; NM_001242830; NM_001242831; NM_001301856
	NM_134255
	NP_001229757; NP_001229759; NP_001229760; NP_001288785; NP_068586
	NP_599016
	Wikidata
View/Edit Human	View/Edit Mouse

Elongation of very long chain fatty acids protein 5 is a protein that in humans is encoded by the ELOVL5 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000012660 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032349 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Leonard AE, Bobik EG, Dorado J, Kroeger PE, Chuang LT, Thurmond JM, Parker-Barnes JM, Das T, Huang YS, Mukerji P (Jan 2001). "Cloning of a human cDNA encoding a novel enzyme involved in the elongation of long-chain polyunsaturated fatty acids". Biochem J. 350 Pt 3 (Pt 3): 765–70. doi:10.1042/0264-6021:3500765. PMC 1221308. PMID 10970790.
^ "Entrez Gene: ELOVL5 ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000012660 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000032349 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10970790-5] Leonard AE, Bobik EG, Dorado J, Kroeger PE, Chuang LT, Thurmond JM, Parker-Barnes JM, Das T, Huang YS, Mukerji P (Jan 2001). "Cloning of a human cDNA encoding a novel enzyme involved in the elongation of long-chain polyunsaturated fatty acids". Biochem J. 350 Pt 3 (Pt 3): 765–70. doi:10.1042/0264-6021:3500765. PMC 1221308. PMID 10970790.

[entrez-6] "Entrez Gene: ELOVL5 ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)".

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