Early intervention in psychosis

Early intervention in psychosis is a clinical approach to those experiencing symptoms of psychosis for the first time. It forms part of a new prevention paradigm for psychiatry[1][2] and is leading to reform of mental health services,[3] especially in the United Kingdom [4][5] and Australia.

This approach centers on the early detection and treatment of early symptoms of psychosis during the formative years of the psychotic condition. The first three to five years are believed by some to be a critical period.[6] The aim is to reduce the usual delays to treatment for those in their first episode of psychosis. The provision of optimal treatments in these early years is thought to prevent relapses and reduce the long-term impact of the condition. It is considered a secondary prevention strategy.

The duration of untreated psychosis (DUP) has been shown as an indicator of prognosis, with a longer DUP associated with more long-term disability.[7]

  1. ^ McGorry PD, Killackey EJ (2002). "Early intervention in psychosis: a new evidence based paradigm". Epidemiol Psychiatr Sci. 11 (4): 237–47. doi:10.1017/s1121189x00005807. PMID 12585014. S2CID 11005414.
  2. ^ McGorry PD, Killackey E, Yung A (October 2008). "Early intervention in psychosis: concepts, evidence and future directions". World Psychiatry. 7 (3): 148–56. doi:10.1002/j.2051-5545.2008.tb00182.x. PMC 2559918. PMID 18836582.
  3. ^ Killackey E, Yung AR, McGorry PD (2007). "Early psychosis: where we've been, where we still have to go". Epidemiol Psychiatr Sci. 16 (2): 102–8. doi:10.1017/S1121189X0000470X. PMID 17619539.
  4. ^ "IRIS History of the development of EI in the UK". Archived from the original on 2012-08-03. Retrieved 2009-12-04.
  5. ^ Joseph R, Birchwood M (September 2005). "The national policy reforms for mental health services and the story of early intervention services in the United Kingdom" (PDF). J Psychiatry Neurosci. 30 (5): 362–5. PMC 1197282. PMID 16151542. Archived from the original (PDF) on 2015-11-17. Retrieved 2009-02-28.
  6. ^ Birchwood M; Tood P; Jackson C (1988). "Early intervention in psychosis: the critical period hypothesis". British Journal of Psychiatry. Supplement 33 (33): 53–59. doi:10.1192/S0007125000297663. PMID 9764127. S2CID 32411917.
  7. ^ Marshall M; Lewis S; Lockwood A; Drake R; Jones P; Croudace T (2005). "Association between duration of untreated psychosis and outcome in cohorts of first-episode patients: a systematic review". Arch Gen Psychiatry. 62 (9): 975–983. doi:10.1001/archpsyc.62.9.975. PMID 16143729.