Easterner may refer to:
- a person from the Eastern world
- a person from the Eastern United States
- Easterner (MP train), a Missouri Pacific train; see List of named passenger trains of the United States (D–H) § E
- Easterner (NYC train), a New York Central train; see List of named passenger trains of the United States (D–H) § E
- Easterners (Korean political faction), a political faction in 16th-century Korea