Ectopic pacemaker

Ectopic pacemaker
Other namesEctopic focus, ectopic foci
An illustration of ectopic foci near papillary muscles in the left ventricle
SpecialtyElectrophysiology, Cardiology
Symptoms
  • Isolated ectopic beats
  • Feeling faint
  • Palpitations

An ectopic pacemaker, also known as ectopic focus or ectopic foci, is an excitable group of cells that causes a premature heart beat outside the normally functioning SA node of the heart. It is thus a cardiac pacemaker that is ectopic, producing an ectopic beat. Acute occurrence is usually non-life-threatening, but chronic occurrence can progress into tachycardia,[1] bradycardia or ventricular fibrillation.[2] In a normal heart beat rhythm, the SA node usually suppresses the ectopic pacemaker activity due to the higher impulse rate of the SA node. However, in the instance of either a malfunctioning SA node or an ectopic focus bearing an intrinsic rate superior to SA node rate, ectopic pacemaker activity may take over the natural heart rhythm.[3] This phenomenon (an intrinsically slower pacemaker activity being unmasked by failure of faster pacemaker tissue 'upstream') is called an escape rhythm, the lower rhythm having escaped from the dominance of the upper rhythm. As a rule, premature ectopic beats (i.e. with a shorter than the prevailing preceding R-R' interval) indicate increased myocyte or conducting tissue excitability, whereas late ectopic beats (i.e. with a prolonged preceding R-R' interval) indicate proximal pacemaker or conduction failure with an escape 'ectopic' beat.

  1. ^ Phibbs, B. (1963). "Paroxysmal Atrial Tachycardia with Block Around the Ectopic Pacemaker: Report of a Case". Circulation. 28 (5): 949–50. doi:10.1161/01.CIR.28.5.949. PMID 14079200.
  2. ^ Tveito, Aslak; Lines, Glenn T. (2008). "A condition for setting off ectopic waves in computational models of excitable cells". Mathematical Biosciences. 213 (2): 141–50. doi:10.1016/j.mbs.2008.04.001. PMID 18539188.
  3. ^ Rozanski, GJ (1991). "Atrial ectopic pacemaker escape mediated by phasic vagal nerve activity". The American Journal of Physiology. 260 (5 Pt 2): H1507–14. doi:10.1152/ajpheart.1991.260.5.H1507. PMID 2035673.