Sir Edward Littleton (c. 1577 – 25 July 1629)[1] was a politician from the extended Littleton/Lyttelton family and an important Staffordshire landowner of the Jacobean era and the early Caroline era. Although loyal to the monarchy, he seems to have been of Puritan sympathies and was a close ally of Robert Devereux, 3rd Earl of Essex. He represented Staffordshire in the English parliament of 1624.