Elisabeth of Hesse may refer to:
- Elisabeth of Hesse-Marburg (1466–1523), daughter of Henry III, Landgrave of Upper Hesse and wife of John V of Nassau-Dillenburg
- Elisabeth of Hesse (1502–1557), daughter of William II, Landgrave of Hesse
- Elisabeth of Hesse (1503–1563), daughter of William I, Landgrave of Lower Hesse and wife of Louis II, Count Palatine of Zweibrücken
- Elisabeth of Hesse (1539–1582), daughter of Philip I, Landgrave of Hesse and married George, Duke of Saxony
- Landgravine Elisabeth Amalie of Hesse-Darmstadt (1635–1709), daughter of George II, Landgrave of Hesse-Darmstadt and wife of Philip William, Elector Palantine
- Elisabeth Henriette of Hesse-Kassel (1661–1683), daughter of William VI, wife of Frederick I of Prussia