Elisabetta Manfredini-Guarmani (2 June 1780 – after 1828) was an Italian opera singer best known for having created the leading soprano roles in four of Rossini's operas, roles which he wrote specifically for her voice.[1] She was born Antonia Elisabetta Manfredini in Bologna and was the daughter of the composer and music theorist Vincenzo Manfredini. After her stage debut in 1810 when she sang in the premiere of Stefano Pavesi's Il trionfo di Gedeone at Bologna's Teatro del Corso, she went on to perform at La Fenice, La Scala, Teatro Regio di Torino, Rome's Teatro Argentina and several other opera houses, primarily in Northern Italy. In addition to the roles she created in Rossini's operas, she also sang in the world premieres of operas by several composers who are lesser known today, including Pietro Raimondi, Simon Mayr, and Ferdinando Paër. Her last known appearance was in 1828 after which there is no further trace of her. The date and place of her death are unknown.