Elizabeth Fry Ashmead Schaeffer (E.F.A. Schaeffer) (February 16, 1812 in Philadelphia, Pennsylvania – November 2, 1892 in Philadelphia, Pennsylvania), was the founder of the Lutheran Home at Germantown for Orphans and an active leader of many ministries of the Lutheran Church in Philadelphia. She was the wife of Rev. Charles William Schaeffer and mother of four children.