Encephalitozoonosis is a parasitic disease caused by the protozoan Encephalitozoon cuniculi, which mainly affects rabbits in Europe. Other strains of the pathogen cause disease in Old World mice and canines. Encephalitozoonosis occurs mainly in immunocompromised animals and is a potential zoonosis. Although very rare, it can also occur in immunocompromised humans. Wright and Craighead first described the disease in 1922.[1]
The pathogen primarily affects the kidneys and brain, causing neurological disorders. The most common symptom is a tilted head. Fenbendazole, an antiparasitic drug, can be used to combat the pathogen and prevent new infections. If clinical symptoms occur, treatment must be extended by administering antibiotics and supportive measures. The prospects of recovery are uncertain.