Enoxacin

Enoxacin
Clinical data
AHFS/Drugs.comMonograph
MedlinePlusa601013
Routes of
administration		Oral
ATC code
Identifiers
  • 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC15H17FN4O3
Molar mass320.324 g·mol−1
3D model (JSmol)
Melting point220 to 224 °C (428 to 435 °F)
  • Fc1c(nc2c(c1)C(=O)C(\C(=O)O)=C/N2CC)N3CCNCC3
  • InChI=1S/C15H17FN4O3/c1-2-19-8-10(15(22)23)12(21)9-7-11(16)14(18-13(9)19)20-5-3-17-4-6-20/h7-8,17H,2-6H2,1H3,(H,22,23) checkY
  • Key:IDYZIJYBMGIQMJ-UHFFFAOYSA-N checkY
  (verify)

Enoxacin[note 1] is an oral broad-spectrum fluoroquinolone antibacterial agent used in the treatment of urinary tract infections and gonorrhea. Insomnia is a common adverse effect.[1][2] It is no longer available in the United States.

Enoxacin may have cancer inhibiting effect.[3]


Cite error: There are <ref group=note> tags on this page, but the references will not show without a {{reflist|group=note}} template (see the help page).

  1. ^ Rafalsky V, Andreeva I, Rjabkova E (July 2006). Rafalsky VV (ed.). "Quinolones for uncomplicated acute cystitis in women". The Cochrane Database of Systematic Reviews. 2006 (3): CD003597. doi:10.1002/14651858.CD003597.pub2. PMC 7003573. PMID 16856014.
  2. ^ Mogabgab WJ (December 1991). "Recent developments in the treatment of sexually transmitted diseases". The American Journal of Medicine. 91 (6A): 140S–144S. doi:10.1016/0002-9343(91)90327-T. PMID 1767802.
  3. ^ Jałbrzykowska K, Chrzanowska A, Roszkowski P, Struga M (June 2022). "The New Face of a Well-Known Antibiotic: A Review of the Anticancer Activity of Enoxacin and Its Derivatives". Cancers. 14 (13): 3056. doi:10.3390/cancers14133056. PMC 9264829. PMID 35804828.