Enterovirus 71

Enterovirus A71
TEM micrograph of Enterovirus 71 virions. Scale bar, 50 nm.
TEM micrograph of Enterovirus A71 virions. Scale bar, 50 nm.
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Pisuviricota
Class: Pisoniviricetes
Order: Picornavirales
Family: Picornaviridae
Genus: Enterovirus
Species:
Enterovirus A
Serotype:
Enterovirus A71
Synonyms
  • Enterovirus 71 (EV71)
  • Human rhinovirus A71
  • Human rhinovirus 71

Enterovirus 71 (EV71), also known as Enterovirus A71 (EV-A71), is a virus of the genus Enterovirus in the Picornaviridae family,[1] notable for its role in causing epidemics of severe neurological disease and hand, foot, and mouth disease in children.[2] It was first isolated and characterized from cases of neurological disease in California in 1969.[3][4] Enterovirus 71 infrequently causes polio-like syndrome permanent paralysis.[5]

  1. ^ "Human enterovirus 71 polyprotein gene, complete cds". 2001-04-30. Archived from the original on 12 December 2014. Retrieved 4 February 2020.
  2. ^ Lin TY, Chu C, Chiu CH (October 2002). "Lactoferrin inhibits enterovirus 71 infection of human embryonal rhabdomyosarcoma cells in vitro". J. Infect. Dis. 186 (8): 1161–4. doi:10.1086/343809. PMID 12355368.
  3. ^ Wang, Jen-Ren; Tuan, Yen-Chang; Tsai, Huey-Pin; Yan, Jing-Jou; Liu, Ching-Chuan; Su, Ih-Jen (January 2002). "Change of Major Genotype of Enterovirus 71 in Outbreaks of Hand-Foot-and-Mouth Disease in Taiwan between 1998 and 2000". Journal of Clinical Microbiology. 40 (1). American Society for Microbiology: 10–5. doi:10.1128/JCM.40.1.10-15.2002. PMC 120096. PMID 11773085.
  4. ^ SY Wang; CL Lin; HC Sun; HY Chen (25 December 1999). "Laboratory Investigation of a Suspected Enterovirus 71 Outbreak in Central Taiwan" (PDF). Epidemiology Bulletin. 15 (12): 215–219. Archived from the original (PDF) on 28 May 2008.
  5. ^ Schubert, Ryan D.; Hawes, Isobel A.; et al. (2019). "Pan-viral serology implicates enteroviruses in acute flaccid myelitis". Nature Medicine. 25 (11): 1748–1752. doi:10.1038/s41591-019-0613-1. PMC 6858576. PMID 31636453.