Enterovirus cis-acting replication element | |
---|---|
Identifiers | |
Symbol | Entero_CRE |
Alt. Symbols | CRE |
Rfam | RF00048 |
Other data | |
RNA type | Cis-reg |
Domain(s) | Viruses |
SO | SO:0000233 |
PDB structures | PDBe |
Enterovirus cis-acting replication element is a small RNA hairpin in the coding region of protein 2C as the site in PV1(M) RNA that is used as the primary template for the in vitro uridylylation.[1][2] The first step in the replication of the plus-stranded poliovirus RNA is the synthesis of a complementary minus strand. This process is initiated by the covalent attachment of uridine monophosphate (UMP) to the terminal protein VPg, yielding VPgpU and VPgpUpU.