Ephrin B2

EFNB2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2HLE, 2I85, 2VSK, 2VSM, 2WO2, 3GXU, 4UF7
Identifiers
Aliases	EFNB2, EPLG5, HTKL, Htk-L, LERK5, ephrin B2
External IDs	OMIM: 600527; MGI: 105097; HomoloGene: 3019; GeneCards: EFNB2; OMA:EFNB2 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	106,535,662 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	8,711,242 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; mucosa of sigmoid colon; ; visceral pleura; ; amniotic fluid; ; parietal pleura; ; periodontal fiber; ; secondary oocyte; ; nipple; ; hair follicle;
	Top expressed in
	lumbar spinal ganglion; ; medullary collecting duct; ; renal corpuscle; ; hair follicle; ; Rostral migratory stream; ; right lung; ; left lung; ; ganglionic eminence; ; vas deferens; ; vestibular membrane of cochlear duct;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	virus receptor activity; protein binding; signaling receptor binding; ephrin receptor binding; protein tyrosine kinase activity;
Cellular component	integral component of membrane; membrane; focal adhesion; plasma membrane; integral component of plasma membrane; Schaffer collateral - CA1 synapse; glutamatergic synapse; integral component of presynaptic membrane; integral component of postsynaptic density membrane;
Biological process	cell differentiation; blood vessel morphogenesis; negative regulation of keratinocyte proliferation; regulation of chemotaxis; cell-cell signaling; anatomical structure morphogenesis; T cell costimulation; lymph vessel development; nervous system development; cell migration involved in sprouting angiogenesis; multicellular organism development; cell adhesion; nephric duct morphogenesis; angiogenesis; animal organ morphogenesis; viral entry into host cell; positive regulation of cardiac muscle cell differentiation; viral process; venous blood vessel morphogenesis; positive regulation of aorta morphogenesis; positive regulation of cell population proliferation; ephrin receptor signaling pathway; axon guidance; negative regulation of neuron projection development; peptidyl-tyrosine phosphorylation; presynapse assembly; regulation of postsynaptic membrane neurotransmitter receptor levels; regulation of postsynaptic neurotransmitter receptor internalization; positive regulation of neuron death;
	Sources:Amigo / QuickGO
Orthologs
	1948
	13642
	ENSG00000125266
	ENSMUSG00000001300
	P52799
	P52800
	NM_004093; NM_001372056; NM_001372057; NM_001372058
	NM_010111; NM_001368299
	NP_004084; NP_001358985; NP_001358986; NP_001358987
	NP_034241; NP_001355228
	Wikidata
View/Edit Human	View/Edit Mouse

Ephrin-B2 is a protein that in humans is encoded by the EFNB2 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000125266 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000001300 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Bonaldo MF, Yu MT, Jelenc P, Brown S, Su L, Lawton L, Deaven L, Efstratiadis A, Warburton D, Soares MB (Sep 1994). "Selection of cDNAs using chromosome-specific genomic clones: application to human chromosome 13". Human Molecular Genetics. 3 (9): 1663–73. doi:10.1093/hmg/3.9.1663. PMID 7833926.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000125266 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000001300 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7833926-5] Bonaldo MF, Yu MT, Jelenc P, Brown S, Su L, Lawton L, Deaven L, Efstratiadis A, Warburton D, Soares MB (Sep 1994). "Selection of cDNAs using chromosome-specific genomic clones: application to human chromosome 13". Human Molecular Genetics. 3 (9): 1663–73. doi:10.1093/hmg/3.9.1663. PMID 7833926.

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