Epimorphosis

For the mathematical function, see Epimorphism.

Epimorphosis is defined as the regeneration of a specific part of an organism in a way that involves extensive cell proliferation of somatic stem cells,[1] dedifferentiation, and reformation,[2] as well as blastema formation.[3] Epimorphosis can be considered a simple model for development, though it only occurs in tissues surrounding the site of injury rather than occurring system-wide.[4] Epimorphosis restores the anatomy of the organism and the original polarity that existed before the destruction of the tissue and/or a structure of the organism.[4] Epimorphosis regeneration can be observed in both vertebrates and invertebrates such as the common examples: salamanders, annelids, and planarians.[5]

  1. ^ "Medical Definition of EPIMORPHOSIS". www.merriam-webster.com. Retrieved 2018-02-19.
  2. ^ Ribeiro RP, Bleidorn C, Aguado MT (March 2018). "Regeneration mechanisms in Syllidae (Annelida)". Regeneration. 5 (1): 26–42. doi:10.1002/reg2.98. PMC 5911452. PMID 29721325.
  3. ^ Yokoyama H (January 2008). "Initiation of limb regeneration: the critical steps for regenerative capacity". Development, Growth & Differentiation. 50 (1): 13–22. doi:10.1111/j.1440-169X.2007.00973.x. PMID 17986260. S2CID 25299267.
  4. ^ a b Kubo T, Arai T (September 1996). "Insect Lectins and Epimorphosis". Trends in Glycoscience and Glycotechnology. 8 (43): 357–364. doi:10.4052/tigg.8.357.
  5. ^ Sánchez Alvarado A, Tsonis PA (November 2006). "Bridging the regeneration gap: genetic insights from diverse animal models". Nature Reviews. Genetics. 7 (11): 873–84. doi:10.1038/nrg1923. PMID 17047686. S2CID 2978615.