| Combination of | |
|---|---|
| Estradiol | Estrogen |
| Norethisterone acetate | Progestogen |
| Clinical data | |
| Trade names | Activella, Amabelz, CombiPatch, others |
| AHFS/Drugs.com | Professional Drug Facts |
| MedlinePlus | a601041 |
| Routes of administration | By mouth |
| ATC code | |
| Legal status | |
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| Identifiers | |
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  (what is this?) (verify) | |
Estradiol/norethisterone acetate (E2/NETA), sold under the brand name Activella among others, is a combination of estradiol (E2) and norethisterone acetate (NETA) which is used in the treatment of vasomotor symptoms, vulvar and vaginal atrophy, and osteoporosis[1] associated with menopause.[2] Activella specifically is marketed by Novo Nordisk and is supplied as film-coated tablets containing 1 mg estradiol and 0.5 mg norethisterone acetate. CombiPatch is a combination of estradiol and NETA provided as a transdermal patch.[2]
- ^ Morabito N, Crisafulli A, Vergara C, Gaudio A, Lasco A, Frisina N, et al. (October 2002). "Effects of genistein and hormone-replacement therapy on bone loss in early postmenopausal women: a randomized double-blind placebo-controlled study". Journal of Bone and Mineral Research. 17 (10): 1904–12. doi:10.1359/jbmr.2002.17.10.1904. PMID 12369794. S2CID 29312298.
- ^ a b "CombiPatch (estradiol/norethindrone acetate transdermal system) Prescribing Information" (PDF). Noven Pharmaceuticals, Inc. U.S. Food and Drug Administration.