FAM120AOS

FAM120AOS
Identifiers
AliasesFAM120AOS, C9orf10OS, family with sequence similarity 120A opposite strand
External IDsHomoloGene: 131283; GeneCards: FAM120AOS; OMA:FAM120AOS - orthologs
Orthologs
SpeciesHumanMouse
Entrez

158293

n/a

Ensembl

ENSG00000188938

n/a

UniProt

Q5T036

n/a

RefSeq (mRNA)

NM_198841
NM_001322224

n/a

RefSeq (protein)

NP_001309153
NP_942138

n/a

Location (UCSC)Chr 9: 93.43 – 93.45 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

FAM120AOS, or family with sequence similarity 120A opposite strand, codes for uncharacterized protein FAM120AOS, which currently has no known function.[3] The gene ontology describes the gene to be protein binding.[4] Overall, it appears that the thyroid and the placenta are the two tissues with the highest expression levels of FAM120AOS across a majority of datasets.

The microarray-assessed tissue expression pattern of multiple normal tissues for FAM120AOS in humans was found using GDS3834 data.[5] The three tissues in the 90th percentile and higher for FAM120AOS gene expression are as follows: the bladder, epididymis, and thyroid. The thyroid is in the 91st percentile, while the other two are in the 90th percentile. Since high thyroid expression was also seen across the RNA-seq data,[6][7][8][9] it appears that FAM120AOS expression may be important in the thyroid.

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000188938 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "AceView: Gene:FAM120AOS, a comprehensive annotation of human, mouse and worm genes with mRNAs or ESTsAceView". www.ncbi.nlm.nih.gov. Retrieved 2020-10-04.
  4. ^ "FAM120AOS family with sequence similarity 120A opposite strand [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2020-10-04.
  5. ^ "GDS3834 / 7875". www.ncbi.nlm.nih.gov. Retrieved 2020-12-18.
  6. ^ Fagerberg L, Hallström BM, Oksvold P, Kampf C, Djureinovic D, Odeberg J, et al. (February 2014). "Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics". Molecular & Cellular Proteomics. 13 (2): 397–406. doi:10.1074/mcp.M113.035600. PMC 3916642. PMID 24309898.
  7. ^ Szabo L, Morey R, Palpant NJ, Wang PL, Afari N, Jiang C, et al. (June 2015). "Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development". Genome Biology. 16 (1): 126. doi:10.1186/s13059-015-0690-5. PMC 4506483. PMID 26076956.
  8. ^ "Illumina bodyMap2 transcriptome (ID 204271) - BioProject - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2020-12-18.
  9. ^ Duff MO, Olson S, Wei X, Garrett SC, Osman A, Bolisetty M, et al. (May 2015). "Genome-wide identification of zero nucleotide recursive splicing in Drosophila". Nature. 521 (7552): 376–379. Bibcode:2015Natur.521..376D. doi:10.1038/nature14475. PMC 4529404. PMID 25970244.