FFAT motif

A FFAT motif (FFAT being an acronym for two phenylalanines (FF) in an acidic tract[nb 1]) is a protein sequence motif of six defined amino acids plus neighbouring residues that binds to proteins in the VAP protein family.[1]


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  1. ^ Loewen CJ, Roy A, Levine TP (May 2003). "A conserved ER targeting motif in three families of lipid binding proteins and in Opi1p binds VAP". The EMBO Journal. 22 (9): 2025–35. doi:10.1093/emboj/cdg201. PMC 156073. PMID 12727870.