FGF7

FGF7
Identifiers
Aliases	FGF7, HBGF-7, KGF, fibroblast growth factor 7
External IDs	OMIM: 148180; MGI: 95521; HomoloGene: 7316; GeneCards: FGF7; OMA:FGF7 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	49,488,775 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	125,933,105 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; stromal cell of endometrium; ; gallbladder; ; epithelium of colon; ; tibial nerve; ; canal of the cervix; ; left uterine tube; ; body of uterus; ; sural nerve; ; ectocervix;
	Top expressed in
	stroma of bone marrow; ; calvaria; ; lobe of cerebellum; ; cerebellar vermis; ; endothelial cell of lymphatic vessel; ; intercostal muscle; ; left lung lobe; ; ankle; ; myotome; ; detrusor urinae muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	heparin binding; fibroblast growth factor receptor binding; protein binding; chemoattractant activity; growth factor activity; 1-phosphatidylinositol-3-kinase activity; protein tyrosine kinase activity; phosphatidylinositol-4,5-bisphosphate 3-kinase activity;
Cellular component	Golgi apparatus; extracellular region;
Biological process	actin cytoskeleton reorganization; mesenchymal cell proliferation; positive regulation of keratinocyte proliferation; positive regulation of epithelial cell proliferation involved in lung morphogenesis; secretion by lung epithelial cell involved in lung growth; positive regulation of epithelial cell proliferation; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling; MAPK cascade; positive regulation of transcription, DNA-templated; fibroblast growth factor receptor signaling pathway; positive regulation of keratinocyte migration; protein localization to cell surface; response to wounding; positive regulation of cell population proliferation; epidermis development; positive regulation of peptidyl-tyrosine phosphorylation; hair follicle morphogenesis; positive chemotaxis; positive regulation of cell division; signal transduction; branching involved in salivary gland morphogenesis; phosphatidylinositol phosphate biosynthetic process; peptidyl-tyrosine phosphorylation; phosphatidylinositol-3-phosphate biosynthetic process; regulation of signaling receptor activity; positive regulation of protein kinase B signaling;
	Sources:Amigo / QuickGO
Orthologs
	2252
	14178
	ENSG00000140285
	ENSMUSG00000027208
	P21781
	P36363
	NM_002009
	NM_008008
	NP_002000
	NP_032034
	Wikidata
View/Edit Human	View/Edit Mouse

Keratinocyte growth factor is a protein that in humans is encoded by the FGF7 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000140285 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027208 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mattei MG, deLapeyrière O, Bresnick J, Dickson C, Birnbaum D, Mason I (Mar 1995). "Mouse Fgf7 (fibroblast growth factor 7) and Fgf8 (fibroblast growth factor 8) genes map to chromosomes 2 and 19 respectively". Mammalian Genome. 6 (3): 196–7. doi:10.1007/BF00293012. PMID 7749227. S2CID 35553603.
^ Kelley MJ, Pech M, Seuanez HN, Rubin JS, O'Brien SJ, Aaronson SA (Oct 1992). "Emergence of the keratinocyte growth factor multigene family during the great ape radiation". Proceedings of the National Academy of Sciences of the United States of America. 89 (19): 9287–91. Bibcode:1992PNAS...89.9287K. doi:10.1073/pnas.89.19.9287. PMC 50111. PMID 1409637.
^ "Entrez Gene: FGF7 fibroblast growth factor 7 (keratinocyte growth factor)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000140285 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027208 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7749227-5] Mattei MG, deLapeyrière O, Bresnick J, Dickson C, Birnbaum D, Mason I (Mar 1995). "Mouse Fgf7 (fibroblast growth factor 7) and Fgf8 (fibroblast growth factor 8) genes map to chromosomes 2 and 19 respectively". Mammalian Genome. 6 (3): 196–7. doi:10.1007/BF00293012. PMID 7749227. S2CID 35553603.

[pmid1409637-6] Kelley MJ, Pech M, Seuanez HN, Rubin JS, O'Brien SJ, Aaronson SA (Oct 1992). "Emergence of the keratinocyte growth factor multigene family during the great ape radiation". Proceedings of the National Academy of Sciences of the United States of America. 89 (19): 9287–91. Bibcode:1992PNAS...89.9287K. doi:10.1073/pnas.89.19.9287. PMC 50111. PMID 1409637.

[entrez-7] "Entrez Gene: FGF7 fibroblast growth factor 7 (keratinocyte growth factor)".

[1]

[2]

[3]

[4]

[5]

[6]

[7]