FIP1L1

FIP1L1
Identifiers
AliasesFIP1L1, FIP1, Rhe, hFip1, factor interacting with PAPOLA and CPSF1
External IDsOMIM: 607686; MGI: 1914149; HomoloGene: 134000; GeneCards: FIP1L1; OMA:FIP1L1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001134937
NM_001134938
NM_030917

NM_001159573
NM_001159574
NM_024183
NM_001376964
NM_001376965

RefSeq (protein)

NP_001153045
NP_001153046
NP_077145
NP_001363893
NP_001363894

Location (UCSC)Chr 4: 53.38 – 53.46 MbChr 5: 74.7 – 74.76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Factor interacting with PAPOLA and CPSF1 (i.e, FIP1L1; also termed Pre-mRNA 3'-end-processing factor FIP1) is a protein that in humans is encoded by the FIP1L1 gene (also known as Rhe, FIP1, and hFip1).[5][6] A medically important aspect of the FIP1L1 gene is its fusion with other genes to form fusion genes which cause clonal hypereosinophilia and leukemic diseases in humans.

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000145216Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029227Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  6. ^ "Entrez Gene: FIP1L1 FIP1 like 1 (S. cerevisiae)".